Osteoclast tartrate-resistant acid phosphatase and osteoblast alkaline phosphatase activities were maintained until 72 h but were reduced at 96 h as a consequence of the massive cell death. Here, we show that gut-specific telomerase activity in tert-/- zebrafish prevents premature aging. This is recapitulated in prematurely aged telomerase mutants ( tert-/- ). The gut is one of the earliest organs to exhibit short telomeres and tissue dysfunction during normal zebrafish aging. On the age composition and the circuli of the black croaker Nibea nibe. Telomere shortening is a hallmark of aging and is counteracted by telomerase.
They often survive to be at least 20 years in age in the wild. The results demonstrate that zebrafish aging is associated with changes in cognitive responses to emotionally positive and negative experiences, reduced generalization of adaptive associations, increased stereotypic and reduced exploratory behavior and altered temporal entrainment. We demonstrated that the cultured scale cells maintained their usual distribution at 28C until 72 h, after which time episquamal osteoblasts showed an obvious change in their cell organization followed by an increase in cell death. Age and growth of a long-lived fish Schizothorax oconnori in the Yarlung Tsangpo. Mountain zebras have similar typical wild lifespans as Burchells zebras. In the present study, we cultured zebrafish scales at various temperatures and for various times and analyzed the behavior of the bone cells in terms of viability and activity. Aged zebrafish have altered expression of the circadian genes zBmal1 and zPer1 but not zClock1. Abstract : Fish scale culture can be used as a model to test the effects of several molecules on bone metabolism by histological and biochemical methods, although solid cell biology data about the behavior of the scale cells in culture are needed if such a model is to be employed for pharmacological applications.
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